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Stem cell 'living bandage' for knee injuries trialed in humans

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Meniscal tears are suffered by over a million folks a yr within the US and Europe alone and are notably widespread involved sports activities like soccer and rugby. Credit score: © ave_mario / Fotolia A 'residing bandage' created from stem cells, which might revolutionise the therapy and prognosis of a typical sporting knee harm, has been trialled in people for the primary time by scientists on the Universities of Liverpool and Bristol. Meniscal tears are suffered by over a million folks a yr within the US and Europe alone and are notably widespread involved sports activities like soccer and rugby. 90% or extra of tears happen within the white zone of meniscus which lacks a blood provide, making them tough to restore. sports activities gamers choose to have the torn tissue eliminated altogether, risking osteoarthritis in later life. The Cell Bandage has been developed by spin-out firm ...

New ultrasound technique is first to image inside live cells

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These are stem cells changing into fats cells. Utilizing the ultrasound approach, we will begin exploring why fats cells placed on fats and whether or not we will make the cells 'food plan' . Credit score: College of Nottingham Researchers at The College of Nottingham have developed a break-through approach that makes use of sound fairly than gentle to see inside stay cells, with potential software in stem-cell transplants and most cancers prognosis. The brand new nanoscale ultrasound approach makes use of shorter-than-optical wavelengths of sound and will even rival the optical super-resolution methods which gained the 2014 Nobel Prize for Chemistry. This new sort of sub-optical phonon (sound) imaging gives invaluable details about the construction, mechanical properties and behavior of particular person residing cells at a scale not achieved earlier than. Researchers from the Optics a...

Researchers confirm molecule's role in kidney formation

Using an innovative screen approach that graduate student Shahram Jevin Poureetezadi designed, the team exposed zebrafish embryos to small molecules, prostaglandin E2, from a chemical library of such molecules known to be active in cell development generally. The researchers wanted to identify small molecules that regulate or modify development. They discovered that activating or interrupting the prostaglandin pathway has a direct impact on the kidney, meaning that it is essential for normal development. The discovery is the culmination of six years of work in the lab, assembling various genes that are important for making kidney cells. Now that the pieces are being connected and the role of prostaglandin is established, Wingert will turn attention to gaining a deeper molecular and mechanistic understanding of how the molecule works in kidney development, especially the gene targets of the signaling. Prostaglandin E2 regulates the formation of blood stem cells and is known to inf...